| UFC 310: Pantoja vs. Asakura | Chase Hooper | 1060 →1079(+19) | Clay Guida | 1002 →983(-19) | Lightweight | Loss | SUB |
| UFC Fight Night: Dariush vs. Tsarukyan | Joaquim Silva | 1009 →1030(+21) | Clay Guida | 1023 →1002(-21) | Lightweight | Loss | U-DEC |
| UFC Fight Night: Holloway vs. Allen | Rafa Garcia | 1010 →1032(+22) | Clay Guida | 1045 →1023(-22) | Lightweight | Loss | U-DEC |
| UFC Fight Night: Thompson vs. Holland | Clay Guida | 1024 →1045(+21) | Scott Holtzman | 1037 →1016(-21) | Lightweight | Win | S-DEC |
| UFC Fight Night: Lemos vs. Andrade | Claudio Puelles | 1060 →1083(+23) | Clay Guida | 1046 →1024(-22) | Lightweight | Loss | SUB |
| UFC Fight Night: Font vs. Aldo | Clay Guida | 1017 →1046(+29) | Leonardo Santos | 1108 →1079(-29) | Lightweight | Win | SUB |
| UFC Fight Night: Cannonier vs. Gastelum | Mark Madsen | 1040 →1060(+20) | Clay Guida | 1037 →1017(-20) | Lightweight | Loss | S-DEC |
| UFC Fight Night: Overeem vs. Volkov | Clay Guida | 1019 →1037(+18) | Michael Johnson | 992 →974(-18) | Lightweight | Win | U-DEC |
| UFC Fight Night: Blaydes vs. Volkov | King Green | 1011 →1032(+21) | Clay Guida | 1040 →1019(-21) | Lightweight | Loss | U-DEC |
| UFC Fight Night: Covington vs. Lawler | Jim Miller | 1067 →1089(+22) | Clay Guida | 1063 →1040(-23) | Lightweight | Loss | SUB |
| UFC 237: Namajunas vs. Andrade | Clay Guida | 1045 →1063(+18) | BJ Penn | 1014 →996(-18) | Lightweight | Win | U-DEC |
| UFC 225: Whittaker vs. Romero 2 | Charles Oliveira | 1050 →1075(+25) | Clay Guida | 1069 →1045(-24) | Lightweight | Loss | SUB |
| UFC Fight Night: Poirier vs. Pettis | Clay Guida | 1045 →1069(+24) | Joe Lauzon | 1063 →1039(-24) | Lightweight | Win | KO |
| UFC Fight Night: Chiesa vs. Lee | Clay Guida | 1025 →1045(+20) | Erik Koch | 1022 →1002(-20) | Lightweight | Win | U-DEC |
| UFC 199: Rockhold vs. Bisping 2 | Brian Ortega | 1053 →1075(+22) | Clay Guida | 1048 →1025(-23) | Featherweight | Loss | KO |
| UFC Fight Night: Belfort vs Henderson 3 | Thiago Tavares | 1050 →1074(+24) | Clay Guida | 1072 →1048(-24) | Featherweight | Loss | SUB |
| UFC Fight Night: Mendes vs Lamas | Clay Guida | 1053 →1072(+19) | Robert Peralta | 1036 →1017(-19) | Featherweight | Win | U-DEC |
| UFC on FOX: Lawler vs Brown | Dennis Bermudez | 1099 →1120(+21) | Clay Guida | 1074 →1053(-21) | Featherweight | Loss | SUB |
| UFC Fight Night: Minotauro vs Nelson | Clay Guida | 1056 →1074(+18) | Tatsuya Kawajiri | 1023 →1004(-19) | Featherweight | Win | U-DEC |
| UFC 164: Henderson vs Pettis 2 | Chad Mendes | 1083 →1106(+23) | Clay Guida | 1079 →1056(-23) | Featherweight | Loss | KO |
| UFC on FOX: Johnson vs Dodson | Clay Guida | 1062 →1079(+17) | Hatsu Hioki | 1019 →1002(-17) | Featherweight | Win | S-DEC |
| UFC on FX: Maynard vs Guida | Gray Maynard | 1134 →1151(+17) | Clay Guida | 1078 →1062(-16) | Lightweight | Loss | S-DEC |
| UFC on FOX: Velasquez vs Dos Santos | Benson Henderson | 1050 →1073(+23) | Clay Guida | 1101 →1078(-23) | Lightweight | Loss | U-DEC |
| The Ultimate Fighter: Team Lesnar vs Team dos Santos Finale | Clay Guida | 1086 →1101(+15) | Anthony Pettis | 1000 →984(-16) | Lightweight | Win | U-DEC |
| UFC 125: Resolution | Clay Guida | 1067 →1086(+19) | Takanori Gomi | 1014 →995(-19) | Lightweight | Win | SUB |
| UFC 117: Silva vs Sonnen | Clay Guida | 1045 →1067(+22) | Rafael Dos Anjos | 1032 →1009(-23) | Lightweight | Win | SUB |
| UFC Live: Vera vs Jones | Clay Guida | 1023 →1045(+22) | Shannon Gugerty | 1001 →980(-21) | Lightweight | Win | SUB |
| UFC 107: Penn vs Sanchez | Kenny Florian | 1127 →1144(+17) | Clay Guida | 1040 →1023(-17) | Lightweight | Loss | SUB |
| The Ultimate Fighter: United States vs. United Kingdom Finale | Diego Sanchez | 1131 →1147(+16) | Clay Guida | 1056 →1040(-16) | Lightweight | Loss | S-DEC |
| UFC 94: St-Pierre vs Penn 2 | Clay Guida | 1032 →1056(+24) | Nate Diaz | 1100 →1076(-24) | Lightweight | Win | S-DEC |
| UFC Fight Night: Diaz vs Neer | Clay Guida | 1010 →1032(+22) | Mac Danzig | 1044 →1022(-22) | Lightweight | Win | U-DEC |
| UFC Fight Night: Florian vs Lauzon | Clay Guida | 986 →1010(+24) | Samy Schiavo | 1000 →976(-24) | Lightweight | Win | KO |
| The Ultimate Fighter: Team Hughes vs. Team Serra Finale | Roger Huerta | 1096 →1113(+17) | Clay Guida | 1003 →986(-17) | Lightweight | Loss | SUB |
| UFC 74: Respect | Clay Guida | 982 →1003(+21) | Marcus Aurelio | 1000 →979(-21) | Lightweight | Win | S-DEC |
| UFC 72: Victory | Tyson Griffin | 1001 →1021(+20) | Clay Guida | 1003 →982(-21) | Lightweight | Loss | S-DEC |
| UFC Fight Night: Evans vs Salmon | Din Thomas | 1023 →1043(+20) | Clay Guida | 1023 →1003(-20) | Lightweight | Loss | U-DEC |
| UFC 64: Unstoppable | Clay Guida | 1000 →1023(+23) | Justin James | 1000 →977(-23) | Lightweight | Win | SUB |
